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"Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less."

- Marie Curie -

Dr. Fattahi's PubMed


Human Induced Pluripotent Stem Cell Derived Sensory Neurons are Sensitive to the Neurotoxic Effects of Paclitaxel.

Xiong, C., Chua, K.C., Stage, T.B., Priotti, J., Kim, J., Altman‐Merino, A., Chan, D., Saraf, K., Canato Ferracini, A., Fattahi, F. and Kroetz, D.L. (2020). Clin Transl Sci.

Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men.

Samuel RM, Majd H, Richter MN, Ghazizadeh Z, Zekavat SM, Navickas A, Ramirez JT, Asgharian H, Simoneau CR, Bonser LR, Koh KD, Garcia-Knight M, Tassetto M, Sunshine S, Farahvashi S, Kalantari A, Liu W, Andino R, Zhao H, Natarajan P, Erle DJ, Ott M, Goodarzi H, Fattahi F. Cell Stem Cell. 2020 Dec 3;27(6):876-889.e12. doi:10.1016/j.stem.2020.11.009. Epub 2020 Nov 17. PMID: 33232663; PMCID: PMC7670929.

Generation of Knockout Gene-Edited Human Intestinal Organoids.

Rajendra C, Wald T, Barber K, Spence JR, Fattahi F, Klein OD. Methods Mol Biol. 2020;2171:215-230. doi: 10.1007/978-1-0716-0747-3_13. PMID: 32705644.

Androgen Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men.

Ghazizadeh Z, Majd H, Richter M, Samuel R, Zekavat SM, Asgharian H, Farahvashi S, Kalantari A, Ramirez J, Zhao H, Natarajan P, Goodarzi H, Fattahi F. bioRxiv [Preprint]. 2020 May 15:2020.05.12.091082. doi: 10.1101/2020.05.12.091082. Update in: Cell Stem Cell. 2020 Nov 17;: PMID: 32511360; PMCID: PMC7263488.

Roadmap for the Emerging Field of Cancer Neuroscience.

Monje M, Borniger JC, D'Silva NJ, Deneen B, Dirks PB, Fattahi F, Frenette PS, Garzia L, Gutmann DH, Hanahan D, Hervey-Jumper SL, Hondermarck H, Hurov JB, Kepecs A, Knox SM, Lloyd AC, Magnon C, Saloman JL, Segal RA, Sloan EK, Sun X, Taylor MD, Tracey KJ, Trotman LC, Tuveson DA, Wang TC, White RA, Winkler F. Cell. 2020 Apr 16;181(2):219-222. doi: 10.1016/j.cell.2020.03.034. PMID: 32302564; PMCID: PMC7286095.


Derivation of enteric neuron lineages from human pluripotent stem cells.
Barber K, Studer L, Fattahi F. Nat Protoc. 2019 Apr;14(4):1261-1279. PMID: 30911172


HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons.

Kishinevsky S, Wang T, Rodina A, Chung SY, Xu C, Philip J, Taldone T, Joshi S, Alpaugh ML, Bolaender A, Gutbier S, Sandhu D, Fattahi F, Zimmer B, Shah SK, Chang E, Inda C, Koren J 3rd, Saurat NG, Leist M, Gross SS, Seshan VE, Klein C, Tomishima MJ, Erdjument-Bromage H, Neubert TA, Henrickson RC, Chiosis G, Studer L. Nat Commun. 2018 Oct 19;9(1):4345. doi: 10.1038/s41467-018-06486-6. PMID: 30341316; PMCID: PMC6195591.

Prospective Isolation of ISL1+ Cardiac Progenitors from Human ESCs for Myocardial Infarction Therapy. 
Ghazizadeh Z*, Fattahi F*, Mirzaei M, Bayersaikhan D, Lee J, Chae S, Hwang D, Byun K, Tabar MS, Taleahmad S, Mirshahvaladi S, Shabani P, Fonoudi H, Haynes PA, Baharvand H, Aghdami N, Evans T, Lee B, Salekdeh GH. Stem Cell Reports. 2018 Mar 13;10(3):848-859. PMID: 29503094. *Equal contribution


A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages.
Tchieu J*, Zimmer B*, Fattahi F*, Amin S, Zeltner N, Chen S, Studer L. Cell Stem Cell. 2017 Sep 7;21(3):399-410.e7. doi: 10.1016/j.stem.2017.08.015. PMID: 28886367. *Equal contribution

Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells.

Qi Y, Zhang XJ, Renier N, Wu Z, Atkin T, Sun Z, Ozair MZ, Tchieu J, Zimmer B, Fattahi F, Ganat Y, Azevedo R, Zeltner N, Brivanlou AH, Karayiorgou M, Gogos J, Tomishima M, Tessier-Lavigne M, Shi SH, Studer L. Nat Biotechnol. 2017 Feb;35(2):154-163. doi: 10.1038/nbt.3777. Epub 2017 Jan 23. PMID: 28112759; PMCID: PMC5516899.


Capturing the biology of disease severity in a PSC-based model of familial dysautonomia.
Zeltner N, Fattahi F, Dubois NC, Saurat N, Lafaille F, Shang L, Zimmer B, Tchieu J, Soliman MA, Lee G, Casanova JL, Studer L. Nat Med. 2016 Dec;22(12):1421-1427. PMID: 27841875

Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease.
Fattahi F, Steinbeck JA, Kriks S, Tchieu J, Zimmer B, Kishinevsky S, Zeltner N, Mica Y, El-Nachef W, Zhao H, de Stanchina E, Gershon MD, Grikscheit TC, Chen S, Studer L. Nature. 2016 Mar 3;531(7592):105-9. PMID: 26863197


Neural Crest Cells from Dual SMAD Inhibition.
Fattahi F, Studer L, Tomishima MJ. Curr Protoc Stem Cell Biol. 2015 May 1;33:1H.9.1-9. PMID: 26344232

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